Dr. Mohammed Enayat, a 41-year-old London-based physician and founder of the HUM2N longevity clinic, has garnered attention for a striking claim: his biological age is just 24, a full 17 years younger than his chronological age.
This remarkable feat is not the result of a miracle cure or a trendy detox but stems from a disciplined, data-driven approach combining advanced diagnostics, personalized lifestyle adjustments, and a focused supplement regimen.
His story offers a compelling glimpse into the emerging field of longevity medicine, where science and technology converge to challenge traditional notions of aging.
Decoding Biological Age: What It Means and How It’s Measured
Biological age attempts to capture the functional state of the body and its cells, reflecting how well—or poorly—our systems are performing relative to our actual years lived. Unlike chronological age, which is simply the number of years since birth, biological age can vary widely among individuals depending on genetics, lifestyle, environment, and health status.
Dr. Enayat’s biological age was assessed using two sophisticated tools: GlycanAge and TruAge PACE. GlycanAge measures inflammation by analyzing glycans—complex sugar molecules attached to proteins that change with age and disease—while TruAge PACE evaluates epigenetic markers, which are chemical modifications influencing gene activity without altering the DNA sequence itself. These tests provide a nuanced picture of aging processes at the molecular level, allowing for targeted interventions.
According to Enayat, his most recent tests, conducted 18 months ago, indicated a biological age of 24, significantly younger than his actual age of 41. This finding underscores the potential to influence aging trajectories through informed lifestyle choices and medical strategies.
A Seven-Year Journey of Self-Experimentation and Precision Health
Dr. Enayat has treated his own body as a living laboratory for over seven years. His approach is deeply rooted in continuous self-monitoring using wearable technology such as the Oura Ring and Whoop strap, devices that track sleep quality, physical activity, heart rate variability, and recovery metrics. These real-time data streams, combined with regular comprehensive laboratory tests—including blood panels, urine analyses, and gut microbiome assessments—allow him to fine-tune his health regimen with precision.
This iterative process of measurement and adjustment exemplifies a modern, personalized approach to health optimization, moving beyond generic advice to strategies tailored to individual physiology and genetic makeup.
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The Core Supplement Trio: Simple Yet Powerful
While Dr. Enayat has access to experimental therapies at his clinic, he emphasizes that his foundational longevity strategy relies on three key supplements taken daily in cycles: a vitamin B complex with folate, magnesium, and omega-3 fatty acids. These supplements address specific physiological needs identified through his testing and are supported by scientific evidence for their roles in health and aging.
Vitamin B Complex and Folate: Supporting Methylation and Cardiovascular Health
A critical factor in Enayat’s regimen is a methylated vitamin B complex combined with folate. He carries a genetic variation affecting his body’s methylation pathway—a biochemical process crucial for DNA repair, detoxification, and regulation of homocysteine, an amino acid linked to inflammation and cardiovascular risk.
Elevated homocysteine levels are associated with increased chances of blood clots, heart attacks, and strokes. By supplementing with methylated B vitamins and folate, Enayat effectively lowers his homocysteine, reducing inflammation and protecting vascular health. This personalized approach highlights the importance of genetic insights in tailoring supplementation.
Beyond cardiovascular benefits, B vitamins contribute to neurological function, mood regulation, and potentially cognitive preservation, though ongoing research continues to clarify these effects. Enayat also notes that even individuals without methylation defects might benefit from methylated B vitamins during periods of stress, poor sleep, or intense physical activity, when the body’s demand for these nutrients rises.
Magnesium: A Multifaceted Mineral for Muscle, Bone, and Metabolic Health
Magnesium plays a vital role in over 300 enzymatic reactions, influencing bone density, muscle contraction, blood sugar regulation, and blood pressure control. Despite its abundance in foods like legumes, leafy greens, nuts, seeds, and whole grains, magnesium deficiency can occur, particularly due to modern dietary patterns.
Enayat’s tests revealed suboptimal magnesium levels, a condition affecting a minority but significant enough to warrant supplementation. He prefers magnesium bisglycinate, a form known for superior absorption and gastrointestinal tolerance. Supplementing with magnesium has helped him reduce muscle soreness and improve sleep quality, benefits that contribute to overall vitality and recovery.
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Omega-3 Fatty Acids: Anti-Inflammatory Agents for Heart and Cellular Longevity
Omega-3 fatty acids, primarily found in oily fish, walnuts, and chia seeds, have long been recognized for their cardiovascular benefits, including lowering inflammation and blood pressure. Enayat’s natural omega-3 status was low, prompting daily supplementation.
While eating fatty fish regularly is well-established as protective against heart disease, the efficacy of omega-3 supplements in replicating these benefits remains under study. Nonetheless, recent research published in Nature Aging involving older adults suggests that consistent omega-3 intake correlates with lower biological age, indicating potential antiaging properties at the cellular level.
Beyond Supplements: A Holistic Framework for Longevity
Dr. Enayat is careful to frame supplements as one component within a broader, integrated health strategy. His regimen incorporates personalized nutrition, exercise, stress management, and continuous health monitoring, all tailored to his unique physiology and lifestyle.
The HUM2N clinic, which he founded, exemplifies this holistic philosophy. It offers advanced diagnostics that go far beyond conventional medicine, analyzing genetic, hormonal, and biochemical markers to uncover hidden health risks before symptoms arise. This proactive model shifts the focus from treating disease to optimizing health and preventing decline.
At HUM2N, patients receive bespoke plans that blend cutting-edge science with lifestyle coaching, aiming to extend not just lifespan but healthspan—the years lived in good health and vitality. The clinic’s futuristic design and patient-centered approach reflect a new paradigm in healthcare, emphasizing empowerment, education, and long-term wellbeing.
The Future of Longevity Medicine: Innovation and Accessibility
Dr. Enayat’s work is at the forefront of a rapidly evolving field that integrates genomics, regenerative medicine, artificial intelligence, and wearable technology. He envisions a future where these tools become widely accessible, enabling individuals to engineer their health proactively and achieve states of resilience and vitality previously thought impossible.
While challenges remain—such as societal adaptation to longer lifespans and ethical considerations—the promise of longevity medicine is profound. It invites a reimagining of aging not as an inevitable decline but as a modifiable process, shaped by knowledge, technology, and intentional living.
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Conclusion: A Model for Modern Aging
Dr. Mohammed Enayat’s experience underscores the potential of personalized, data-driven health strategies to influence biological aging. His disciplined use of targeted supplements—vitamin B complex with folate, magnesium, and omega-3 fatty acids—combined with rigorous self-monitoring and a comprehensive lifestyle framework, offers a practical blueprint for those seeking to optimize their health trajectory.
While no single approach guarantees youthfulness, Enayat’s journey illustrates how science-informed habits, continuous learning, and proactive care can meaningfully impact how we age, adding not just years to life but life to years. As longevity medicine advances, stories like his illuminate the path toward a future where aging is met with vitality, resilience, and hope.
